Differential gene expression profile in the small intestines of mice lacking pacemaker interstitial cells of Cajal

Abstract Background We previously Hard Top Headliners / Deadeners identified eight known and novel genes differentially expressed in the small intestines of wild type and W/WV mice, which have greatly reduced populations of the interstitial cells of Cajal, that are responsible for the generation of electrical slow waves, by using a differential gen

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The essential role of CCT2 in the regulation of aggrephagy

Protein aggregation, a defining characteristic of numerous human diseases, poses a significant challenge to cellular health.Autophagy, an essential cellular recycling process, specifically targets and degrades these harmful protein aggregates through a specialized mechanism known as aggrephagy.However, the precise mechanisms underlying the exquisit

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An Exoskeleton Robot for Human Forearm and Wrist Motion Assist

The exoskeleton robot is worn by the human operator as an orthotic device.Its joints and links correspond to those of the human body.The same system operated in different modes can be used for different fundamental applications; a human-amplifier, haptic interface, rehabilitation device and assistive device sharing a portion of the external load wi

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